Manufacture of chemical and allied products

Oligogen, Inc

Oligogen, Inc

Many central nervous system diseases lack effective treatments, and regenerative medicine is considered one promising solution. Oligodendrocytes are cells that produce insulator structures called myelin to assist neuronal signal transduction, and at the same time, their progenitor cells regulate microglia to suppress inflammation in the brain. Therefore, we have developed human neural stem cells "OligoGenie" that differentiate into oligodendrocyte progenitor cells/oligodendrocytes with almost 100% efficiency. These cells are considered suitable for regenerative medicine because they can be produced in large quantities at very low cost, are resistant to freezing and thawing, and have a high safety profile. We are currently preparing for clinical trials using "OligoGenie.
Area of Interest
  • North America
  • Europe

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SDGs we are working on
3.Good health and well-being

Registered Keyword
Features and Characteristics of Human Neural Stem Cell "OligoGenie"
1. OligoGenie differentiate into neurons, astrocytes, and oligodendrocytes in the presence of serum
2. OligoGenie differentiate into oligodendrocyte progenitor cells or oligodendrocytes with near 100% efficiency in the absence of serum.
3. When transplanted into the brain of normal animals, OligoGenie survive for a long period of time in the oligodendrocyte progenitor cell state.
4. When transplanted into the brain of demyelinating disease models, OligoGenie differentiate into oligodendrocytes and repair myelin
5. 10- to 20-fold proliferation in culture in one week, with a potential of approximately 30 passages.
6. Highly safe, as somatic stem cells have a very low risk of becoming cancerous.
7. Very high cell survival rate after freezing and thawing
8. Easy culture and low production cost

Treatment Mechanism
Human Neural Stem Cell "OligoGenie"
In vitro differentiation of OligoGenie
Non-clinical Proof of Concept (PoC)
Treatment Strategies and Target Diseases